GRB7, GRB10 AND GRB14, ENCODING THE GROWTH FACTOR RECEPTOR-BOUND 7 FAMILY OF SIGNALLING ADAPTOR PROTEINS HAVE OVERLAPPING FUNCTIONS IN THE REGULATION OF FETAL GROWTH AND POST-NATAL GLUCOSE METABOLISM

Grb7, Grb10 and Grb14, encoding the growth factor receptor-bound 7 family of signalling adaptor proteins have overlapping functions in the regulation of fetal growth and post-natal glucose metabolism

Abstract Background The growth factor receptor bound protein 7 (Grb7) family of signalling adaptor proteins comprises Grb7, Grb10 and Grb14.Each can interact with the insulin receptor and other receptor tyrosine kinases, where Grb10 and Grb14 inhibit insulin receptor activity.In cell culture studies they mediate functions including cell survival, p

read more

Signifance of Liver Ductal Plate Malformation in Differential Diagnosis of Autosomal Recessive Polycystic Kidney Disease: An Autopsy Case

Cystic Window Squeegees renal diseases are a group of disorders that cause neonatal deaths.Autosomal recessive polycystic kidney disease (ARPKD) is a rare entity which may be associated with liver disorders.Presenting autopsy case was stillbirth in 31 + 1 gestational week.In postmortem autopsy,viewed through the capsule, the renal surface was fille

read more

A validated method to assess the network length and the heat distribution costs of potential district heating systems in Italy

The evaluation of the district heating network investment costs requires knowledge of its topology.However, when assessing district heating potential, the topology is not known a priori and a simulation is required.One method for the generation of simulated networks involves the use of Minimum Spanning Tree, from the graph theory.In Foot Files this

read more

Predictive Ability of Future Anxiety in Professional Decision-Making Skill among a Syrian Refugee Adolescent in Jordan

This study aimed to examine how and to what extent future anxiety contributes to the level of professional decision-making skills among Syrian refugee students in the tenth grade in public schools in Jordan for the year 2018/2019.Using a quantitative approach, 227 tenth-grade Syrian refugee students in public schools in the University Embroidery Fa

read more